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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e9e8342ba9f57c68c846d6bddfb7f5d7660cfbe1f8d41d5f72b0afbe068456' 
  AND token = 'QmL6c3Zq7qKNE+pmo2jEtz9g33GG2uKO9ep4ZN/4acw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}