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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '790ea153cee5a2d7fe657c0dbf03e9e67deca5b4ed4e65a82861e84531c12fe7' 
  AND token = '0LoBGlhiSfLDLrWVAKcNpS3WvaN0g16Leap6FY/IakA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}