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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf81bcda9e974dd8ac9a369f5e191324f6498f64c055b7f3a3b72e6985f430e8' 
  AND token = 'DKSNTRqne5a1yEBhyMSGxnAT304TFaUN7GBfVU6faOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}