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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c24cda0f90087d46fd1b11392b9e13d51a1def1c4e614e7030817adda9be37' 
  AND token = '1Z3kFjETnCmVBjArmv7CNimI7OQlOZrMs1p27XwKJlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}