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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c404dee4319c2a3fab52ddcce3ebfc1feefc1594cc74a356ccff3d7796f234' 
  AND token = '6tCurcToQui7BmfLYWSdOejluf21/PzHgyu0SH0dz50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}