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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186c3e21cf5da8bcf8b6825b0a68144e2249d18c6521210a412b955ce245d53a' 
  AND token = 'JDLLqdNbimhpde158H2jaQTl/FIlifvdW043IUwRjFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}