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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e735e946f092bdc9c324f9ba0d16d82800d46cff35c9f22b71540b65124d8620' 
  AND token = 'PtxbjHOSO0Gfu4aMLwKdwzehWsYqLcbW/PJZrTuPseM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}