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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad249cdea879168fc5b857f30b454a94c8ed72c30c61cc1c81efe36f1e0e510a' 
  AND token = 'tx3Rgk30oQjkGStBYSBcdK9sHJRUCyzdsPLQYy+LWI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}