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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1645415e98b0a2878c904b3ee6f068c251dd75297cae467d87f78dabc3492c49' 
  AND token = 'csRnUOZKOdPZYuIbrB7dON2ApdIQ0Sn72bGAlrvsBpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}