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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5d3ceaf19d4b19fa20ba36009f280877b85a6d0144bbf4906b89d8baed7f1b3' 
  AND token = 'i41jmwjM708g7r+r/jqO7okcuprDwsaXgcwHGpQHREA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}