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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b822b125ae0d2a6c5f341a75643b3298ef0093def7ca5679b9e2ac3725486a77' 
  AND token = 'LBQBc+vhVg7U7tMKzq7hCfEqQlsnHhQec1CWcu5zfho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}