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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eea00489348b1a781b120c017d8d0c433ecfdcd2f2241e76d3be8c3e8718b417' 
  AND token = 'WUJIxjFjboA7MdfX2bEMxrpKkyMYuSJ8an/gkRwUH9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}