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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f21147cac86106250d86f17951f391254eaad4fa8e5131d7b247f88029a8ff66' 
  AND token = 'hP0h7kInoA2vk9xWnFvy+bCqSs0AmnQtXshUb0A9wKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}