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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1591b0fecf17be7b288868355b3892fe9d12b4f06a09aca4213c96140a4437a4' 
  AND token = 'RfuY4C7tQaA1/hr/0l93XNRapJYGJkatK74EkSdhQCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}