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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b59211c790261d9c6d495e18063b305022a1ff3a9be9c7b8878e2ae6c3419d' 
  AND token = 'FWHIV/C62VxbaQ9WAmX0PbLuhQ0fL47UmCKIa0K0e/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}