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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4ead32122a23736be964f66c8ede7d9effade23ff1f2e03114f24922c5400f' 
  AND token = 'eFww/TOV4V5q/msm61SVM9d4pYGij9aIZYpNS/254dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}