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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03d8203211d249c4d81d0240519c3e0506d17bb4e4047d9e38ea35fe5a9fa2a4' 
  AND token = 'tW89IDU8jd4AWmcBOQbFetvKnjprTBvle4WuCe6NFVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}