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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad9f21f7c2655a214e3be121e3209b1e6c56d48af680370758323036d2577e51' 
  AND token = '7YYmLAW6ZEbsMOI6bevMaDbhSPFyAqrHuuXQ4XEF6Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}