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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8c243b47fa0fd04851ac6eb8c39130947bb280700d86e4e3bd5cd00c241d6be' 
  AND token = '6+JzudwOo3vIIXrhDvjpVWNxWXAIDseRSZKL9ksfD28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}