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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a3b10362f3269d5d3bbd7af87d9a3d1626dd248add92f9431699acf8d69467' 
  AND token = 'w5kKV8CtIRkvu/AMHr41NiW6w3w0V0K1PFPFnLxoLZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}