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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed040f2c5fd6347e4f12144d6be66c164f4e72ba5eaaa856b7dcbbac8c382e3f' 
  AND token = 'njBLAXc+9uT2pzffchw1x1583CmGpJFuOpcq/BnDsao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}