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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e655b1e4ac24f8d7d4d8018a30e622cb0d11ca7ea5d04b36d12efcc1b74bb73' 
  AND token = 'QNfg63PiTPD+Y808d/CPEmf0OAbXfTfxI8h7MWb+tf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}