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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '181977c422b2f461b5a9a11cf98ab06c626870bfbc754dfa1cd92e24447dac21' 
  AND token = 'SvkO5krB41J5Mpa38/C2He4LvqPN45hsF/eJBFF1gss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}