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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a45765f2b3f37b6e0bd7e05c8e576fd087d2bd38f0732500f3891418faa3bcee' 
  AND token = 'kOwnHhxwWfkvubNTsCLu3DAnjZAD7D6ttpu8A+eeIj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}