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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9268c8f50a21e32897133b3e69758f61edd897c7278c6c22a16075cc05831398' 
  AND token = 'X32Khj36scj+7btL8oIedf+EmVVBDjJTDUdTtnI+mWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}