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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ef0fac5cad2fca122c660477f9651a10b5d27e21443e210d1dcba45ea434554' 
  AND token = 'XmvfLY5T19IGhQj7xq+47lmuSxz3n82fkYhAavqymbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}