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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b80525b2203cecaed0ddfce7ef8139752b5359f9094fe4585251b305134b83' 
  AND token = 'OJ3jgLH4xnPw39PyepK0i9TF1TWFDRVBuYqW5xqPM3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}