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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0a0f29cd0e477b8f681366376930869038aa0c5098021297a1dc3c5937a28f9' 
  AND token = 'lUJ57E+G1x4DTQzXmb6aou4/VaWY/PlIOMK+GnKyMHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}