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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c486a731c98ecc9e3440e21c30233293b601962c928432cbc1d3e8aece5669cd' 
  AND token = '69jO1VDez/47iesqi3Js7wwkywAXfpV2xuaySFa1NDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}