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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f33a1f1a4275ed9c82c15cfa66d789bf3af17adb4c8a755a1f0e997b54e4ce93' 
  AND token = 's6Oad6Dggq5VVmSH11g+NpOPw85KRFwFxgjR2nKCGdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}