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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60541368cea94d7428dc7d1d44dc520c99e1ae132a27b2a02c036e69ed390797' 
  AND token = 'YmeSrRXlLvdTAaaFlcvVhODTNXvtth2BPhRpw1BveoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}