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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac912fa735bd5a75f68069401c3cfa67a44dfa9621bf785d8c77688ae733e7a' 
  AND token = '/rRgBnuG/iHLIl1T8gP9lPV/cHWMCzYDYe9oxbnldrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}