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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37edd53a0a2de344ba98fd673726ec61f73089f7d590bae3165dd7e5c99785fd' 
  AND token = '16obET7DVL9ZNPt4x+zeoyDeiJpCcDI4/qOtwPf8CV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}