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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7cd3e3124fb298f27d1b284ec94e66cfdcd3fa11d4bea792914964bbb596fa6' 
  AND token = 'qmPFvpy/G8pHSj+HoSRQEu8C+O11m9X/SnrvcayChhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}