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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e9d3e1d6905141c309438e3cefbc7d216a3f7672ae187d8f14531c29fe9fdd' 
  AND token = 'zxAVNlC+CHU1Y8Ne3Jouo4KyNCv5Frt36gbwCoEs/fA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}