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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433f85e6f9dabc527ca9121e31702c009f8b6c04c8f7a41715d6fea0fbfc19f7' 
  AND token = 'PCladqflTAxHc4/YztqzbOFbQnUp9EpS6QiB8avqJUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}