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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2974763a7cc01851d71508132e19d8394277ad95000957cddcbdd592e234b0d' 
  AND token = '1HP4dWwpH2sN6/H+vUmrJ7JcLJp1aYJWnKPSm/1ZRSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}