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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa0282e572cfca332d8af11e94d11207b82376107394897bd94c254695e6d009' 
  AND token = 'FU6A+VJzzd0XseElgq3+RXnS9Tm2x4EaIkyd+QHQ4wE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}