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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42e033aa59a9d09699cee82f5c88f254a17ec341aa2625afbbd8af1c13567583' 
  AND token = 'BTlp9UVYlOH38ySZX88/DZye1HUYzt58oAC+F9hZoHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}