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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1505592ef2ab13ba2369bb2d813c44fffd9ac4a3e65164ce86f1584b4a78f2' 
  AND token = 'cjO20XOuGEoVrJKsCo521oDfjXwvKoY1ghelI1JCTjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}