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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81fb329bf19c4d309f09fd89c3d6d70d03f0c8c35465b3e39b119c3e344c119' 
  AND token = '1E3geivaLtQc2GynN4DfnSFMLdd/TF3+OrnJMb985bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}