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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a8a11ec152bec51b06c5949269235f99215985a8c4f08345f8679ea1b23c9f2' 
  AND token = 'gIerfb3Wk3n3OZrSiq+pSQxpSNv6JlIqAws9oxuNanQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}