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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40d5567435350c6f3d8f1eea1e5f8998d41934b4b4af7a1e5a547ef15f01c653' 
  AND token = 'STdukG+oa/rbB0ExSCwUWV5BNZh4n2zwIdRPIwPXdws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}