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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29a5dfd01501c31ef482acad2ce4c5f7d94abb5139d21c4d36622b0d546fde27' 
  AND token = 'ELZ3dawltTQ7a7BQO85hLAJGtGv7HO43+M9NFqr5vek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}