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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53dc584ed08b46e5124a3322c1ac585392304897e7cfc550764b14f28a56bf85' 
  AND token = '7i2BvsQY+6CrAGa/6y6m80ys7OYWTpbyYPUl0T5MIHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}