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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '176640effc08a3dccf080a99235f8dee1c9e173c4e047f3da545a86ae89b04a8' 
  AND token = 'XgPxZFCUK3cmMv+Q0A37tCri3TAKHsKogKxibwh54KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}