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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91298c19f53ab58e0dee42b2780d8077337694f2490a06d8c496c4fbbe35a0ca' 
  AND token = 'UO0pu+L7n46F1635A7AuHxRIN1mo65fmjhWRqXtNC8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}