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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f9a0fddb487d8cc51fc08190f216432be5ffd6e282488b4da5a450b88fa741d' 
  AND token = 'rUGY84BawOcj0nY+gaN+E6Jv374/eo2wwjw0yFZC4Mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}