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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e5fe0e5b7451a96435b9db4d57dac2fa11efb54f3897100448ef078222858d' 
  AND token = 'AZzk7rI7Ax18Hx2IW2zRvyEJgletdCGkU8oyEp6X21c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}