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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '623303062c328235cad464688190b0a9255abf350522690e0870f34485a7eb30' 
  AND token = 'DGil+sV+GxPpKk41vsQ5dzufaktueiM9cnkDgH0U6Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}